Hemoglobin-Based O2 Carrier O2 Affinity and Capillary Inlet pO2 Are Important Factors That Influence O2 Transport in a Capillary
نویسندگان
چکیده
منابع مشابه
Increased hemoglobin O2 affinity protects during acute hypoxia.
Acclimatization to hypoxia requires time to complete the adaptation mechanisms that influence oxygen (O(2)) transport and O(2) utilization. Although decreasing hemoglobin (Hb) O(2) affinity would favor the release of O(2) to the tissues, increasing Hb O(2) affinity would augment arterial O(2) saturation during hypoxia. This study was designed to test the hypothesis that pharmacologically increa...
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Recent experimental and theoretical results show that the collision pairs, O2⋅O2 and O2⋅N2, absorb a small but significant fraction of the globally incident, solar radiation (Pfeilsticker et al. 1997, Solomon et al. 1998, Mlawer et al. 1998). The contribution of the water vapor dimer to shortwave (SW) absorption, however, remains speculative due to uncertainties in both its abundance and its ab...
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In previous calculations of how the O2 transport system limits .VO2(max), it was reasonably assumed that mitochondrial P(O2) (Pm(O2)) could be neglected (set to zero). However, in reality, Pm(O2) must exceed zero and the red cell to mitochondrion diffusion gradient may therefore be reduced, impairing diffusive transport of O2 and .VO2(max). Accordingly, we investigated the influence of Pm(O2) o...
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ژورنال
عنوان ژورنال: Biotechnology Progress
سال: 2007
ISSN: 8756-7938
DOI: 10.1021/bp0700298